GHRP-6 & GHRP-2 Peptide Therapy

GHRP-6 and GHRP-2 are part of a family of peptides known as growth hormone releasing peptides (GHRPs). These compounds stimulate the body’s own production of growth hormone, which may support muscle growth, fat metabolism, recovery and overall wellness. At The Catalyst Clinic, we offer expert consultation and medical supervision for those exploring peptide therapy, including GHRP-6 and GHRP-2.

What are GHRP-6 and GHRP-2?

  • GHRP-6 – a synthetic peptide (hexapeptide) that stimulates growth hormone release by binding to the ghrelin receptor. It is known for its strong appetite-stimulating effects.

  • GHRP-2 (Pralmorelin) – another synthetic peptide in the same family, also stimulating GH release via the ghrelin receptor, but with a slightly different profile and fewer appetite-related effects.

Both peptides act as secretagogues, meaning they trigger the body to release more of its own growth hormone rather than supplying it directly.

Benefits of GHRP-6 and GHRP-2

Studies and clinical observations suggest that both peptides may offer:

  • • Increased growth hormone secretion – leading to higher circulating GH levels
  • • Muscle growth & repair – GH supports protein synthesis and recovery
  • • Fat metabolism – GH stimulates lipolysis (fat breakdown)
  • • Improved bone density – supporting skeletal strength and mineralisation
  • • Enhanced recovery & wound healing
  • • Better sleep quality – growth hormone plays a role in restorative sleep
  • • Neuroprotective & cardioprotective effects (early research)

GHRP-6 specific benefits:

  • • Strong appetite stimulation (helpful for those needing increased caloric intake)
  • • Possible anti-inflammatory effects

GHRP-2 specific benefits:

  • • Cognitive support (linked to GH’s role in memory and learning)
  • • Potential immune and cardiovascular health benefits

How Do GHRP-6 and GHRP-2 Work?

Both peptides bind to the growth hormone secretagogue receptor (GHS-R1a), the same receptor activated by the natural hormone ghrelin. This binding triggers a cascade of signals that lead to a surge in natural growth hormone release from the pituitary gland.

The result is a boost in GH activity, which supports tissue growth, fat metabolism, and repair processes throughout the body.

Potential Therapeutic Applications

GHRP-6 and GHRP-2 are being studied for potential roles in:

  • • Supporting recovery from injury or surgery
  • • Age-related decline in GH and muscle strength
  • • Weight management and metabolic health
  • • Bone density support
  • • Immune and cardiovascular health research

Note: Both peptides are investigational and classed as research compounds. Human evidence is limited, and they are not licensed medications.

Safety and Side Effects

Both peptides are generally well tolerated but may cause:

  • • Increased hunger (more pronounced with GHRP-6)
  • • Water retention or mild bloating
  • • Numbness/tingling in extremities
  • • Fatigue or headaches
  • • Possible changes in prolactin levels

Long-term effects remain under study, particularly around insulin sensitivity and glucose metabolism. At The Catalyst Clinic, peptide therapy is only provided after full consultation and under medical supervision to minimise risks.

Treatment Process at The Catalyst Clinic

1

Consultation

A detailed discussion of your goals, health history, and suitability for therapy.

2

Personalised Plan

If appropriate, a tailored peptide programme including GHRP-6 and/or GHRP-2.

3

Ongoing Monitoring

Regular reviews, progress tracking, and safety checks.

Our international clinics in London, New York, and Zurich provide access to advanced peptide therapy with expert support.

 FAQs

  • They are studied for supporting growth hormone release, muscle repair, fat metabolism, and recovery.

  • They are similar but not identical. Both release GH, but GHRP-6 is known for stronger appetite stimulation, while GHRP-2 may have additional cognitive and cardiovascular research benefits.

  • Short-term use appears generally well tolerated, though more research is needed on long-term safety. Side effects are usually mild.

  • Yes. The Catalyst Clinic offers consultations and supervised peptide therapy, including GHRP-6 and GHRP-2, at our London clinic.

Book a Consultation

Interested in GHRP-6 or GHRP-2 peptide therapy?
Contact The Catalyst Clinic in London, New York, or Zürich today to book your consultation.