VIP Peptide Therapy for Autoimmune and Inflammatory Disorders

Rebalancing Immunity and Restoring Cellular Harmony

Autoimmune and inflammatory conditions — from rheumatoid arthritis (RA) to inflammatory bowel disease and chronic pulmonary inflammation — arise when the immune system loses its natural equilibrium. The result is ongoing tissue damage, fatigue, and progressive dysfunction.

At The Catalyst Clinic, we utilize VIP (Vasoactive Intestinal Peptide) therapy to restore immune tolerance at a cellular level. VIP is a naturally occurring neuropeptide that orchestrates anti-inflammatory, vasodilatory, and immunomodulatory effects — offering a biologically elegant way to calm immune overactivity while enhancing repair and regeneration.

How VIP Works

VIP binds to VPAC1 and VPAC2 receptors throughout the nervous, immune, and vascular systems, triggering cAMP-mediated signalling cascades that suppress inflammatory cytokines and promote regulatory immune balance.

This powerful mechanism results in:

  • Downregulation of TNF-α, IL-1β, and IL-6 — central to autoimmune inflammation
  • Enhanced IL-10 signalling for immune tolerance
  • Relaxation of smooth muscle and improved vascular oxygenation
  • Stabilisation of endothelial integrity, reducing oxidative and inflammatory stress

In both research and clinical practice, VIP therapy has shown promise in:

  • Rheumatoid arthritis and autoimmune arthropathies
  • Inflammatory bowel disease (Crohn’s, ulcerative colitis)
  • Chronic Inflammatory Response Syndrome (CIRS)
  • Pulmonary arterial hypertension (PAH) and post-COVID inflammation
  • Neuroinflammatory conditions including multiple sclerosis and neurodegenerative disease

Clinical Integration at The Catalyst Clinic

At The Catalyst Clinic, VIP Peptide Therapy forms part of our advanced immune recalibration protocols. It is administered under medical supervision using precision microdosing to optimise receptor responsiveness and minimise systemic stress.

VIP may be delivered:

  • Subcutaneously to influence systemic immune and vascular balance
  • Intranasally for neurological or respiratory indications
  • In combination with KPV, BPC-157, or ARA-290, depending on the patient’s immune profile and inflammatory phenotype

Our clinicians begin with comprehensive biomarker mapping — including cytokine panels, endothelial function testing, and autonomic balance assessment — to design a tailored peptide strategy for sustained remission and tissue recovery.

The Catalyst Advantage

Healing begins when the immune system learns balance — not suppression.

At The Catalyst Clinic, VIP therapy embodies our regenerative ethos: targeted, intelligent, and deeply restorative.

By reprogramming immune communication and vascular tone, VIP helps the body shift from chronic inflammation toward equilibrium — enhancing energy, cognition, and resilience from within.

Book a Consultation

Contact The Catalyst Clinic in London, New York, or Zürich today to book your consultation.