Tesamorelin Peptide Therapy

Tesamorelin is a growth hormone–releasing hormone (GHRH) analogue that stimulates the body’s natural production of growth hormone (GH). By boosting GH levels, Tesamorelin helps improve metabolism, body composition, and overall vitality. At The Catalyst Clinic, we offer expert consultation and personalised peptide therapy plans that may include Tesamorelin.

What is Tesamorelin?

Tesamorelin is a synthetic peptide that mimics the action of natural GHRH.

  • Mechanism: It binds to receptors in the pituitary gland, encouraging the release of GH.

  • IGF-1 Increase: Higher GH levels raise insulin-like growth factor 1 (IGF-1), which regulates cell growth, repair, and metabolism.

  • Clinical recognition: Tesamorelin is FDA-approved for reducing excess abdominal fat in people with HIV-related lipodystrophy.

In simple terms: Tesamorelin tells the body to make more of its own growth hormone, with benefits for fat reduction, lean muscle support, and metabolic health.

Benefits of Tesamorelin

Research and clinical use suggest Tesamorelin may support:

  • • Reduction of visceral abdominal fat – especially effective in reducing fat stored deep around organs
  • • Improved metabolic health – supports better insulin sensitivity and energy balance
  • • Muscle maintenance – helps preserve lean muscle mass
  • • Body composition improvements – favourable ratio of fat loss to muscle retention
  • • Anti-ageing potential – investigated for offsetting natural age-related GH decline
  • • Quality of life improvements – higher GH levels may support energy, physical performance, and overall wellbeing

How Tesamorelin Works

Tesamorelin mimics natural growth hormone–releasing hormone (GHRH).

  • • Stimulates the pituitary gland to secrete more growth hormone
  • • Increases circulating IGF-1, which contributes to fat metabolism, muscle repair, and tissue regeneration
  • • Unlike direct GH therapy, Tesamorelin encourages the body to produce GH naturally, which may reduce risks of hormone imbalance

Potential Therapeutic Applications

Tesamorelin is being studied or used in the following contexts:

  • • FDA-approved: treatment of lipodystrophy in HIV patients
  • • Visceral fat reduction – improving central fat distribution and body composition
  • • Metabolic support – aiding energy balance and insulin sensitivity
  • • Age-related decline – explored as an anti-ageing intervention
  • • Fitness and recovery – potential role in performance and rehabilitation (under research)

Note: Outside of its approved use, Tesamorelin is considered investigational and should only be used under medical supervision.

Safety and Side Effects

Tesamorelin is generally well tolerated but may cause:

  • • Mild injection site reactions (redness, swelling, itching)
  • • Joint pain or stiffness
  • • Increased IGF-1 levels (requires monitoring)
  • • Rarely, fluid retention or fatigue

At The Catalyst Clinic, we provide full medical oversight, including regular check-ups and monitoring, to ensure safe and effective treatment.

Treatment Process at The Catalyst Clinic

1

Consultation

We assess your health history and goals.

2

Personalised Plan

If suitable, Tesamorelin may be included in your peptide therapy programme.

3

Ongoing Monitoring

Regular reviews ensure safety, effectiveness, and progress tracking.

Our clinics in London, New York, and Zurich offer international access to advanced peptide therapy.

 FAQs

  • It is FDA-approved for treating lipodystrophy in people with HIV and is also studied for fat reduction, metabolic health, and anti-ageing.

  • No. Tesamorelin stimulates the body to produce more of its own GH, whereas HGH therapy provides direct synthetic growth hormone.

  • It is usually administered via subcutaneous injection.

  • Yes. The Catalyst Clinic offers consultations and supervised peptide therapy including Tesamorelin at our London clinic.

Book a Consultation

Explore whether Tesamorelin peptide therapy could support your health and body composition goals.
Contact The Catalyst Clinic in London, New York, or Zürich today to book your consultation.