KPV Peptide Therapy for Rheumatoid Arthritis

A Next-Generation Approach to Autoimmune Inflammation

Rheumatoid arthritis (RA) is an autoimmune condition defined by chronic inflammation, joint pain, and progressive tissue destruction. Traditional therapies often suppress the immune system broadly — alleviating symptoms but at the cost of long-term balance and resilience.

At The Catalyst Clinic, we approach RA through a regenerative and systems-biology lens. KPV (Lysine–Proline–Valine)represents a groundbreaking class of bio-regulatory peptides that help the body modulate inflammation naturally, restoring immune harmony and protecting joint integrity without the burden of heavy immunosuppression.

How KPV Works

KPV is a tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH) — one of the body’s most potent endogenous anti-inflammatory molecules.

By inhibiting NF-κB, a central driver of inflammatory cytokine release, KPV reduces TNF-α, IL-1β, and IL-6 — all key mediators of rheumatoid pathology.

Simultaneously, KPV enhances regulatory immune signalling (IL-10 and TGF-β), stabilises endothelial and epithelial barriers, and mitigates oxidative stress — creating an internal environment conducive to repair rather than attack.

Clinical Integration at The Catalyst Clinic

At The Catalyst Clinic, KPV is offered as part of a precision-targeted peptide protocol designed for patients with autoimmune or chronic inflammatory conditions such as RA.

Depending on the case profile, KPV may be administered:

  • Subcutaneously, to promote systemic anti-inflammatory effects
  • Orally or transdermally, for localised immune modulation
  • In combination with BPC-157, VIP, or ARA-290, for synergistic repair and immunologic balance

Each programme begins with advanced immune, metabolic, and peptide receptor profiling, enabling a fully personalised treatment map aligned with each patient’s inflammatory signature.

The Catalyst Advantage

Where conventional medicine aims to suppress, we aim to recalibrate.

KPV therapy exemplifies the Catalyst philosophy — leveraging the body’s innate mechanisms of balance, precision, and repair to restore optimal function from within.

Our integrative approach combines molecular diagnostics, precision dosing, and longevity-focused follow-up to ensure measurable improvement in joint mobility, energy, and quality of life.

Book a Consultation

Contact The Catalyst Clinic in London, New York, or Zürich today to book your consultation.